YOUTH IS HIDDEN
WITHIN YOUR CELL

What is Exomine?

Exomine stresses the platelets and trace amounts of other blood cells contained in PRP, causing the secretion of billions of vesicles. At the same time, it activates platelets with its special protocol and devices and provides a plasma rich in platelet-derived exosomes.

EXOMINE, which has a wide range of usage in Aesthetic, Orthobiological and Therapeutic applications, provides effective results in many areas such as skin regeneration, hair loss, spot treatments, joint and connective tissue treatments, and non-healing wounds.

AUTOLOGOUS SYSTEM
SAFE AND EFFECTIVE

Exomine Kit is an autologous system obtained from the patient’s own blood, so it does not cause any side effects such as allergic reactions or immune system problems after injection. Exomine Kit product provides safe and effective application for the patient.

EXOMINE: A LEADER IN EVERY MEDICAL SPECIALTY

In Joint and Connective Tissue Treatments
Through the functions of intercellular signaling and cell stimulation, it contributes to the augmentation of synovial fluid, It plays a significant role in strengthening and repairing joint and connective tissue.

In Hair and Skin Treatments
Nourishing the hair tissue and stimulating hair follicle cells significantly stops hair loss, promotes the growth and thickening of existing hair. By stimulating the production of essential collagen and elastin for the skin, it enhances skin texture, reduces the appearance of wrinkles, and facilitates quick repair and regeneration.

EXOMINE, A PIONEER IN AESTHETICS

The Exomine Kit induces the release of billions of vesicles by stressing platelets and trace amounts of other blood cells found in PRP. Simultaneously, it provides a plasma rich in platelet-derived exosomes by activating platelets with its special protocol and devices.

mRNA: Through its support in transferring genetic information to target cells, it plays a critical function in facilitating intercellular communication and the exchange of genetic material.

miRNA: Through the modulation of gene expression, it governs the synthesis of proteins, proving effective in biological processes like cell differentiation, development, and regulation.

Protein: It provides intercellular communication and regulation.

NOT EVERY VESICLE IS AN EXOSOME,
DISCOVER THE UNIQUENESS!

MICROLYSER BLADE TECHNOLOGY
The Microlyzer 600μm, with its special design blades and structure, induces the release of billions of vesicles by stressing blood cells and plays a significant role in the activation of platelet cells simultaneously.

 

ADVANCED PRX TUBE
T-LAB, through collaborative efforts with its highly skilled research and development team collaborating with specialized medical professionals, has developed patented and uniquely designed ”Advanced PRX Tube” as a result of studies aimed at enhancing vesicle release of blood cells of specific size and weight. With its special internal design, the product facilitates the release of billions of vesicles, activation of platelet cells, and settling of trace amounts of other blood cells in the pellet.

Billions of Vesicles, Optimum Size, High Viability!

EXOMINE reaches approximately 4-5 billion vesicles per mL, as a result of the device and protocol studies carried out by T-LAB. EXOMINE, whose final product is approximately 5cc, offers its users an average of 25-30 billion vesicles, the highest number of vesicles in its field.

In order for vesicles to be defined as exosomes, their size must be between 30-150nm, they must be analyzed with relevant CD markers and their viability must be high. In line with the studies conducted with EXOMINE, unbiased laboratory results have proven that the average vesicle size is 116nm, as a result of the analyzes performed with the relevant CD markers, 98% of the vesicles are platelet-derived exosomes and the viability is 99%.

 

PROVEN PROTOCOL

RESULTS OF NANOSIGHT NS300 NTA

RESULTS OF FLOW CYTOMETRY

CD9 (Platelet) : 99,6%
CD45 (Pan Leukocyte Marker) : 0,3%
CD41 (Platelet GPIIb, IIb Integrin) : 99,4%
CD61 (Platelet glycoprotein GPIIIa) : 98,6%
CD81 (Target for anti-proliferative antigen 1 [TAPA-1]) : 98,5%
7 AAD : 98,9%

Immunophenotypic measurements were performed using the Beckman Coulter DxFLEX Flow Cytometry system, and the evaluation was completed with the CytExpert DxFLEX software program. (Measurements were implemented at the Private Deren Laboratory.)

As a result of the studies carried out, 4.5 × 10 9  particles/mL vesicles were obtained with the EXOMINE Kit, the average vesicle size was 116.6 nm, and as a result of the analyzes carried out with the relevant CD markers, 98% of the vesicles were exosome origin and the viability was 99%. proven by its results.

USAGE AREAS

AESTHETICS

EXOMINE has a wide potential for use in the fields of Aesthetic and Plastic Surgery, Dermatology and Medical Aesthetics. It is frequently used in combination with skin and fat tissue to ensure soft tissue healing, regionally improving tissue quality, gaining tissue shine, increasing elastin and collagen synthesis, eliminating wrinkles and hair loss. It is used in dermatology, especially for skin rejuvenation, wrinkle removal, stretch mark and blemish treatments. EXOMINE ensures thickening, volume and growth of hair follicles in the area for weakened hair and is widely used after hair transplantation.

ORTHOBIOLOGICS

EXOMINE’s most important purpose in the field of Orthopedics and Physical Therapy is; It allows patients to continue their daily lives comfortably by relieving pain and reducing the number of applications requiring drug injection and surgical interventions. In general, tendinosis (at the cellular level, chronic tendon damage), improvement of ligament and connective tissue damage, positive effect of fascia (plantar fasciitis), known as fibrosis-related tissue, and Achilles tendon damage, cartilage damage and bone-related damage (BMSCs combinations). It is frequently used for this reason.

THERAPEUTICS

In wound care; Successful results can be obtained with EXOMINE in cases where surgical options are limited or the success rate of surgery is low, such as wounds due to vascular insufficiency, wounds opened on the basis of trauma (provided that they are not cancerous) or sugar sores.
In Ophthalmology, known as ophthalmology, EXOMINE is used especially in cases of Corneal Ulcer and Dry Eye syndrome. However, for example, in dry eye syndrome, the prepared EXOMINE is applied by the drip method instead of the injection method. It is known that EXOMINE helps prevent inflammation in corneal ulcers.
In Oral and Maxillofacial Surgery, EXOMINE is effective in stimulating bone and hard tissue as well as soft tissue. It is used clinically in many areas, from gums to jaw bone osteonecrosis.